EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ASSOCIATION BETWEEN VITAMIN D AND STROKE: A CASE- CONTROL STUDY

Dr. Chandan Sharma and Dr. Ashima Badyal

ABSTRACT

Background: Globally every second person has a poor vitamin D status, which a public health problem of real concern. Reduced plasma 25(OH) D concentrations as a diagnostic marker of vitamin D deficiency have been associated with risk factors for ischemic stroke. The aim of this study was to compare serum 25- hydroxyvitamin D (25(OH) D) levels in acute stroke patients and healthy subjects. Method: A Case-Control Study was conducted in the Department of Medicine, GMC Jammu, during a period of one year, on 70 patients with stroke incidence and 70 age and gender matched healthy controls. Results: The mean age was 60.55 ± 12.46 years and 60.37 ± 12.02 years in cases and controls respectively. A statistically significant difference was observed in the mean body mass index (BMI), between cases and controls. The most common risk factor was found to be hypertension with 81.43% of cases. The median value of serum 25(OH) Vitamin D level was 9.06 ng/mL in the cases and 10.89 ng/mL in controls. The difference between the serum 25(OH) vitamin D levels of the two groups, even in sub group analysis, was not statistically significant; however, patients more than 65 years of age showed the lowest levels of 25(OH) Vitamin D amongst all with a median value of 8.03 ng/mL and IQR of 4.45-16.16 ng/mL. Conclusion: No significant association was found between low Vitamin D levels and cases of ischemic or haemorrhagic stroke, but the beneficial effects of Vitamin D supplementation can’t be ignored.

Keywords: Background: Globally every second person has a poor vitamin D status, which a public health problem of real concern. Reduced plasma 25(OH) D concentrations as a diagnostic marker of vitamin D deficiency have been associated with risk factors for ischemic


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia