‘A NOVEL ANALYTICAL METHOD DEVELOPMENT BY HPLC, HPTLC AND UV TECHNIQUE FOR ACTIVE PHARMACEUTICAL INGRADIENTS IN FORMULATIONS’
Patil Rohit* and Ashpak Tamboli
ABSTRACT
In this study, the author has developed a HPTLC method for the estimation of Chlorthalidone in Commercial brand CTD-12.5 of Chlorthalidone. The values obtained suggested that the proposed HPTLC method was simple, precise, rapid and robust for determination of ketoconazole. The mobile phase was simple to prepare and economical. The authors then validated the method as per ICH guidelines and correlated the obtained values with standard values. Satisfactory result were obtained.
Keywords: HPTLC method, Chlorthalidone, CTD-12.5.
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