EVALUATION OF ANTI-VIRAL ACTIVITY OF BANLEC AGAINST HEPATITIS C VIRUS
*Areez Hafiz Md. Zahid
BanLec is a mannose binding lectin derived from Musa acuminata (banana). It is known to have drug potential against HIV and current studies are working on its efficacy against AIDS. In this study, using in silico methods, the binding efficiency of BanLec against Hepatitis C virus has been tested and positive interactions with BanLec have been observed. Furthermore, mutational analysis using bioinformatics tools in BanLec show interesting and more tentative results with Hepatitis C virus.
Keywords: Banana lectin, mannose-binding lectin, in silico studies, HCV, liver cirrhosis.
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