EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

STUDY ON ANTIMICROBIAL USE IN SURGICAL PROPHYLAXIS

Sriram A.*, Junior Sundresh N. and Dheepthi M.

ABSTRACT

Objectives: To observe and document the commonly used prophylaxis in this study. To observe and document the antimicrobials used to treat post-surgical infections. To observe the total consumption of antimicrobials used in the study using defined daily dose. Methods: This is cross-sectional study conducted in rajah muthaih medical college it is based on ASHP therapeutic guidelines for antimicrobial prophylaxis in surgery. Results: This result comprises 150 samples were admitted in surgery ward and investigated prospectively. Among that women were more in number with 54.67% than men with 45.33%. The majority of the patients were with an age group of 20-30 years (42.60%), 31-40 years (24%), 41-50 years (10%), 51-60 years (23.4%) were admitted in the surgery wards. In this study, the most commonly occurring surgery was appendicitis (60%), followed by inguinal hernia (13.3%), wound debridement (10%) hydrocele (6.7%), abscess left thumb (6.7%) and gastric perforation (2.7%) were mainly admitted for surgery. The most commonly used antimicrobial prophylaxis in this study was said to be Cefotaxime (58%) and ceftriaxone (27%) in this study. The antimicrobial agents which was prescribed to treat post-surgical infections in most of the cases was Gentamycin which was given to 32% of the cases followed by 22.7% patients were prescribed metronidazole, while 21.3% patients received Cefixime, a third generation cephalosporin and amikacin 16% were used along with the above antimicrobials. Conclusion: Third generation cephalosporins were considered as the most commonly used prophylaxis in this study. Gentamycin, metronidazole and Cefixime were used to treat post-surgical infections. Metronidazole, Cefixime and ciprofloxacin were frequently observed in surgical patients during hospital discharge. There is a need of hospital specific guidelines for antimicrobial use in choosing prophylaxis and proper counseling were needed for the patients in this study. Optimal timing of antibiotic administration is considered an important factor for effective prophylaxis.

Keywords: Antimicrobials, Prophylaxis, Surgical site infections.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database