EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

PRELIMINARY STUDIES ON PHYTOCHEMISTRY AND IN VITRO ANTIMICROBIAL ACTIVITY OF EXTRACTS OF CNIDOSCOLUS ACONITIFOLIUS

K. J. Kiran*, Rakesh Kumar Jat and J. Jaslin Edward

ABSTRACT

The present study was aimed to evaluate the phytochemical and antimicrobial nature of the different extracts of the leaves of Cnidoscolus aconitifolius plant. Initially, the plant leaves was collected authenticated and dried for powdering. The dried material was powdered in mechanical grinder and the coarse powder thus obtained was extracted in soxhlet apparatus with the solvents of increasing polarity viz., petroleum ether, chloroform, ethyl acetate and methanol. The dried extracts thus obtained were used for the preliminary phytochemical evaluation and antimicrobial activity studies viz., antibacterial and antifungal evaluation. The results of preliminary phytochemical evaluation revealed the presence of alkaloids, glycosides, phenolic compounds and tannins, flavanones and flavonoids, terpenoids, and saponins. The methanol and ethyl acetate extracts showed a significant presence of majority of phytochemicals comparing with other two, the petroleum ether, chloroform extracts. In the evaluation of antimicrobial activity, the methanol extract showed a significant antibacterial and antifungal activity against tested pathogens particularly P. vulgaris, S. aureus, and Aspergillus sp. These results are useful for further investigation in the future.

Keywords: Cnidoscolus aconitifolius, preliminary phytochemical evaluation, antimicrobial evaluation.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia