BACTERIOLOGICAL PROFILE AND ANTIBIOTIC SENSITIVITY PATTERN OF DIABETIC FOOT ULCER AT TERTIARY CARE CENTER, JAMNAGAR, GUJARAT.

Dr. Pushpa R. Kateshiya, Dr. Binita J. Aring* and Dr. Dipali M. Gavali

ABSTRACT

Introduction: World’s largest number of Diabetes Mellitus is present in India. Most common complication due to diabetic foot ulcer is lower limb amputation.Diabetic foot ulcer is polymicrobial with multidrug resistant. AIMS & Objectives: This study was to isolates thebacterial pathogens and their antibiotic susceptibility pattern from discharge samples from patients with diabetic foot ulcer in microbiology department at tertiary care hospital, Jamnagar. Materials & Methods: 171(57%) isolates were recovered from wounddischarge samples 300.Antibiotic susceptibility of microorganism was determined by using disk diffusion method as per CLSI guidelines. Result: Amongst 300 samples 171(57%) were positive for bacteriological culture, in which major isolates was Pseudomonas 44 (25%), followed by Proteus spp. 38 (22%), E.coli 29 (17%), Klebsilella spp. 27 (15%), S.aureus 27 (15%) and Acinetobacter 11 (6%). Among all gram negative bacilli were sensitive to Imipenem 100%, followed by Piperacillin-tazobactam 67%, followed by Gentamicin 49%. Among all gram positive cocci Vancomycin and Erythromycin were sensitive 96%, followed by Linezolid 93%. Conclusion: This study shows that in Diabetic foot ulcer most common organism was Pseudomonas followed by Proteus spp., E.coli, etc. Early identification of organism can help to treat with right antibiotic & help early recovery.

Keywords: Diabetes Mellitus, Foot ulcer, Bacteria, Antibiotic susceptibility test.