A REVIEW: PROMISING TECHNOLOGY FOR EFFECTIVE TOPICAL DELIVERY OF DRUGS

Vivek Verma* and Dr. T. S. Easwari

ABSTRACT

A Nanoemulgel is a nanoparticle composed of a hydrogel—a crosslinked hydrophilic polymer network. Nanogels are most often composed of synthetic polymers or biopolymers which are chemically or physically crosslinked. Nanogels are usually in the tens to hundreds of nanometers in diameter. Like hydrogels, nanogels have low density of macromolecules and their pores (spaces between the macromolecular chains) can be filled with small molecules or macromolecules, and their properties, such as swelling, degradation, and chemical functionality, can be controlled. Current review deals with the study to for finding nanomeulgel a promising technique for topical delivery of poorly water soluble drugs. Some latest researches concluded that nanogels formulation has proven bioavalibility and safety issues to those drugs which are available in traditional formulations and their adverse effects are of major concern. Nanoemulgels are also overcome the solubilty issues to poorly water soluble drugs. Latest studies have started gaining interest of researchers with nanogels as they are non-greasy, better patient compatibility and easy spreadibilty and good therapeutic efficacy and safety.

Keywords: Nanoemulsion, Nanoemulgels, Nanogels, Drug delivery.