EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

WOUND HEALING ACTIVITY AND ANTI ULCER ACTIVITY OF ETHANOLIC EXTRACT OF PEELS OF ANANAS COMOSUS

Sowjanya K.*, Spandana U., R.R. Manjula, Havilah Esther S., Sravani T. and G. Shiva Nageswara Rao

ABSTRACT

Aim: To study the “wound healing” & “anti ulcer” activity of ethanolic extract of peels of Ananas comosus. Objectives: Prepare ethanolic extract of peels of Ananas comosus, to perform phyto chemical screening studies & evaluation of wound healing, anti-ulcer activities. Methods: The wound healing & anti-ulcer efficacy of ethanolic extract of peels of Ananas comosus was evaluated in excision wound model and aspirin induced ulcer method. The rats were divided into 4 groups with 6 rats in each group. Group 1 rats were treated with vehicle. Group 2 rats were treated with standard drug. Group 3 and 4 rats were treated with extract at 100 and 200mg/ kg bd wt respectively. Results: The percentage healing with Ananas comosus peel extract was significantly higher than standard from the 2nd day of treatment and continued till the completion of the treatment. The extract has a tremendous potential as a natural potent and safe alternative to conventional antiulcer treatment. Conclusion: The ethanolic extract of peels of Ananas comosus showed significant wound healing & anti-ulcer activity which is evident by the data obtained.

Keywords: Wound healing; anti-ulcer; ethanolic extract; Ananas comosus peel.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia