VERY EARLY ONSET- INFLAMMATORY BOWEL DISEASE (VEO-IBD) IN A THREE YEARS OLD CHILD: A CASE REPORT

Bodhrun Naher*, Md. Rafiqul Islam, Sharmistha Ghosal and Khan Lamia Nahid

ABSTRACT

Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract, and its pathogenesis involves genetic and environmental factors. Inflammatory bowel disease (IBD) that presents in children <6 years of age is known as very early-onset IBD (VEO-IBD). Since childhood-onset IBD seems to be a more aggressive and rapidly progressive disease than adult-onset IBD, it should therefore be diagnosed and treated immediately. This subgroup is often characterized by higher severity, aggressive progression, strong family history of IBD, predilection for colon-only involvement, and poorer response to conventional treatments. Immunodeficiencies are identified in up to 25% of cases, which may impact response, safety, and indication to different therapies. Here, we report a case of very early-onset IBD (VEO-IBD) in a three years old boy with clinical and biochemical manifestations. The diagnosis was confirmed with histopathological evidence.

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