EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

LABORATORY SPECTRUM OF COVID-19 PATIENTS AND VARIATIONS WITH CO-MORBIDITIES: A STUDY IN TERTIARY CARE HOSPITAL OF NORTHERN INDIA

Sumeet Sidhu*, Gurpreet Bahia and Gurpreet Singh Battu

ABSTRACT

Background: The first case of Coronavirus Disease 2019 (COVID-19) was described in Wuhan, December 2019. The virus has evolved into a pandemic over a short period of time with rapidly increasing cases and associated morbidity and mortality. Laboratory parameters like inflammatory markers and tests of fibrinolytic pathway play an important role in diagnosis and prognostication of the disease. Methods: It is a retrospective observational study. One hundred and fifty four hospitalized patients with diagnosis of COVID-19 over a period of 2.5 months were enrolled in the study. Laboratory parameters, presenting complaints and co-morbidities were recorded and studied. Statistical analysis was done using percentage, mean and two tailed T test. Results: The median age of presentation was 57.5 years. Lymphopenia was observed in 48.7% and thrombocytopenia in 24% cases. Amongst inflammatory markers, serum Ferritin was raised in 81.7%, Interleukin-6 in 76.4% and C-reactive protein in 99.2% of the patients. D-dimer analysis showed raised levels in 80.3% patients. The median age of patients with co morbidities was 61.26 years as compared to earlier presentation at 52.37 years in cases with no underlying disease (p value 0.000152). Patients with co-morbidities were associated with statistically significant higher C-reactive protein levels (p value 0.0318) and higher absolute neutrophil count (p value 0.039). Differential counts showed lower lymphocyte counts (p value 0.0329) and higher neutrophil counts (p value 0.0499) in patients with co-morbidities.

Keywords: COVID, co-morbidities, D-dimer, Inflammatory markers.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )