EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

EVALUATION OF ADHERENCE TO MEDICATION IN PATIENTS OF PSORIASIS: TOPICAL VERSUS SYSTEMIC THERAPY

*Dr. Smita Sontakke, Dr. Mitali Wagh, Dr. Nikita Ingale, Dr. Jayesh Mukhi, Dr. Vijay Motghare and Dr. Mrunalini Kalikar

ABSTRACT

Aim: To evaluate adherence to medication and to compare adherence to topical and systemic therapy in patients of psoriasis. Methods: This was a prospective, cross-sectional, questionnaire-based study carried out in patients of psoriasis on treatment for at least three months. Study subjects were interviewed by direct face-to-face interview and information entered in semi-structured, open-ended questionnaire. Adherence was also assessed by Morisky 4-item medication adherence scale. The same patient was evaluated separately for adherence to topical and systemic medication. Results: Significantly more number of patients followed medication schedule for systemic medicines(70.3%) compared to topical(50.5%) (p=0.03) In both groups, most common type of non-adherence was: not buying all medicines. Number of patients who thought that not taking systemic medicines would adversely affect the disease was significantly more than those who thought the same about topical medicines(p=0.007). Most common reasons for not following medication schedule were: high cost of medicines, forgetfulness, and complex dosing schedule. Antihistaminics were the most preferred systemic medication and Calcipotriol 0.005% and clobetasol 0.05% combination was the most preferred topical medication. Conclusion: Rate of high adherence was significantly more with systemic medications compared to topical in the same patients. Majority of patients believed that not using the systemic medicines would more adversely affect the disease and hence they were more adherent to systemic therapy compared to topical. Hence, when prescribing topical treatments, it is important to emphasize upon the patients the importance of being adherent to medication as this is important for effective and long term control of psoriasis.

Keywords: MMAS-4, Morisky 4-item medication adherence scale, cross-sectional study.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )