ANALYTICAL TECHNIQUES FOR THE ESTIMATION OF PHARMACEUTICAL DRUGS IN PURE AND TABLET DOSAGE FORMS
Pratik Paricharak* and Ashpak Tamboli
ABSTRACT
A reverse phase high performance liquid chromatography (RP-HPLC) method for the analytical techniques for the estimation of pharmaceutical drug in pure and tablet dosage forms developed. Chromatography carried out 30ºC temperature on Agilent Zorbax Bonus RP (250×4.6 mm,5μ) Column. Column using Mobile Phase 0.1% Perchloric acid and ACH in ratio {60:40}) withflow rate 1ml/min. Validation parameter such as System sutability, Linearity, Recovery, Accuracy, LOD&LOQ. In that injection volume 10μl. In that HPLC wavelength is 234nm.
Keywords: Chlorthalidone, RP-HPLC.
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