ISOLATION AND CHARACTERIZATION OF SECONDARY METABOLITES FROM FLOWER METHANOL EXTRACT OF CATHARANTHUS ROSEUS

Shahin Aziz* and Koushik Saha

ABSTRACT

Catharanthus roseus is an important medicinal plant in Bangladesh. The plant is administered as a cooling medicine. From methanol extract 5 Compounds: ajmalicin (1), catharanthine (2), 3,3',4',5,7-Pentahydroxyflavone or Quercetin (3), Quercetin-3-O-rutinose or Rutin (4) & benzoic acid (5) have been isolated from flowers Catharanthus roseus. The structures of the compounds have been established by different spectroscopic data analysis. Compounds Quercetin-3-O-rutinose or Rutin (4) and benzoic acid (5) were isolated for the first time from flowers as well as from of the plant C. roseus.

Keywords: Catharanthus roseus, isolation, structure elucidation, spectroscopic methods.