( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Sh. K. Muminov*


Purpose of the study: to determine the risk factors for the development of CKD in patients with coronary artery disease (CAD) after myocardial revaslarization. Material and methods. The study included 160 patients with coronary artery disease who underwent coronary angiography. The study included patients with eGFR over 60 ml / min. On the second day after the endovascular procedure, the patients underwent determination of the blood creatinine concentration to identify patients who developed contrast-induced nephropathy (CIN). In dynamics, at the end of the second year of follow-up all patients underwent repeated examination. Research results. CIN in the early period after endovascular intervention was observed in 37 patients. All patients with CAD included in the study were distributed depending on the eGFR achieved by the end of the 2nd year after revascularization. In 20% (32 out of 160) patients, an eGFR of less than 30 ml / min was achieved. Comparative analysis of the parameters revealed that patients with the worst prognosis in terms of the development of CKD were significantly older (p <0.01), they initially had more impaired renal filtration function (p <0.001). Conclusion. The most significant prognostic marker for the development of CKD IV-V in patients with coronary artery disease within 2 years after revascularization is the development of contrast-induced nephropathy in the early period after endovascular intervention (increases the risk of CKD IV-V by 7.31), the concentration of BNP in the peripheral blood serum is more than 587 pg / ml (increases the risk of CKD IV -V 10.16 times), LVEF less than 52% (increases the risk 9.72 times) and the sphericity index more than 0.62 units (increases the risk 8.77 times).

Keywords: chronic kidney disease, ischemic heart disease, contrast-induced nephropathy, echocardiography.

[Full Text Article]




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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia