EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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 ICV - 79.57

Abstract

SERUM CALCIUM IN PRIMARY POSTPARTUM HAEMORRHAGE

Oguaka V. N., Adinma J. I. B.*, Okafor C. I., Udigwe G. O., Adinma Obiajulu-ND and Edet M. M.

ABSTRACT

Background: Postpartum haemorrhage may cause maternal mortality. Uterine atony is a major cause of primary post-partum haemorrhage (PPH). Calcium plays a role in uterine contraction and may contribute to the causation of uterine atony. Objective: To determine the serum calcium levels in parturient women and its relationship to primary PPH. Subject and Method: A cohort study of 140 consecutive parturient women at Nnamdi Azikiwe University Teaching Hospital, Nigeria, involving intrapertum estimation of serum calcium levels and relating it to primary PPH. Data analysis was done using SPSS version 21.0. Comparison of variables employed student’s t-test, with p-values of <0.05 at 95% confidence interval considered to be statistically significant. Results: of the 140 parturient, 97 (69.3%) had Spontaneous Vertex Delivery (SVD); 25 (17.9%), assisted delivery, and 18 (12.9%), caesarean section. Sixteen (11.4%) women (all with SVD) had primary PPH, 10 (62.5%) of which were due to uterine atony. The mean serum ionized calcium level of participants without primary PPH was higher (1.11±0.25 mmol/L) than that of participants who had primary PPH from uterine atony (1.0±0.35 mmol/L), (P = 0.037). Conclusion: This study shows that hypocalcaemia occurred in parturient women with primary PPH from uterine atony. Suggesting the role of adequate calcium in preventing obstetrics haemorrhage. The relationship between serum calcium and primary PPH could be explored in the development of predictive, preventive and therapeutic strategies for primary PPH and ultimate reduction of maternal morbidity and mortality from PPH.

Keywords: Serum calcium, uterine atony, primary post-partum haemorrhage, parturient women.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )