EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECT OF LURASIDONE ON POSITIVE SYMPTOMS IN SCHIZOPHRENIA PATIENTS IN RURAL SETTING IN INDIA: A LONGITUDANAL STUDY

Darshan Yallappa Jotibannad Dr. Gaurav Uppal*, Dr. Aseem Garg, Dr. P. D. Garg and Dr. Shiny Dehal

ABSTRACT

Background and objectives: New antipsychotics have modified the course of schizophrenia. Not many medications have shown improvement in negative symptoms, and psychological shortages, compounded by unbearable results. Lurasidone is a moderately new participant in the field of schizophrenia in the Indian setting. This investigation assessed the general viability of Lurasidone across positive symptoms of schizophrenia. Methods: This is a longitudinal observational investigation. PANSS was administered at the time of admission, first month and following 3 months. An aggregate of 57 patients, analyzed utilizing ICD-10 standards, were selected, from the psychiatry OPD of MVJ Medical College and Research Hospital. 7 patients left because of grievousness. Measurable examination of the information was done on the SPSS (Statistical Package for Social Sciences Software). Utilizing suitable measurable techniques, dimensional examinations were made utilizing the focal propensities like the Mean with Standard Deviations for Lurasidone. T- test was applied for finding out the significance of ‘p’ values where appropriate. Results: In positive scale of PANSS, mean decrease of positive score toward the finish of multi week was 6.13, toward the finish of 3 months the mean positive score was 10.9.The current investigation showed that Lurasidone has impact on certain manifestations of schizophrenia at week 4 and better adequacy at week 12. By and large outcomes show better reaction to positive symptoms. Anyway a more drawn out follow up would help us study the impact of Lurasidone on the course of schizophrenia.

Keywords: Lurasidone; efficacy; Indian population; schizophrenia; positive symptoms.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )