EVALUATION OF LIPID PROFILE LEVEL AMONG HEALTHY SUBJECTS AND THEIR RELATION WITH OBESITY

Dr. Vibhuti Patoria*, Dr Sanyyam Guglani and Dr. Prashant Gajjar

ABSTRACT

background and Aim: The rising prevalence of obesity in India has a direct correlation with the increasing prevalence of obesity-related co-morbidities; hypertension, the metabolic syndrome, dyslipidemia, type 2 diabetes mellitus (T2DM), and cardiovascular disease (CVD). The present study was conducted to assess lipid profile level among healthy subjects and their relation with obesity. Material and Methods: The present study was conducted in department of Medicine. It comprised of 300 healthy subjects of both gender. General information such as name, age, gender etc. was recorded. In all subjects, height, weight and BMI were calculated. Their total cholesterol, triglycerides, low density lipoproteins, high density lipoproteins and very low density lipoproteins was studied. Results: Mean cholesterol in males was 181.5 mg/dl and in females was 166.4 mg/dl, HDL was 40.8 mg/dl in males and 51.1 mg/dl in females, LDL was 111.5 mg/dl in males and 99.1 mg/dl in females, VLDL was 23.5 mg/dl in males and 22.3 mg/dl in females. The difference was significant (P< 0.05). There was significant higher level of lipid profile in obese subjects as compared to healthy subjects. The difference among males and females was significant (P< 0.05). Conclusion: Obesity is associated with lipid disturbances, especially with HDL-C reduction as compared to healthy subjects. Health education and more preventive measures should decrease the prevalence of obesity and cardiac risks by modifying their lifestyle.

Keywords: Cardiovascular disease, Cholesterol, High Density Lipoproteins, Obesity.