SYNTHESIS OF 3-SUBSTITUTEDIMINO-5-[2-ISOBUTOXY-5-(4-METH- YL-5- CARBOXY-1,3-THIAZO-2-YL)-PHENYLFORMAMIDINO]AMINO 1,2,4-DITHIAZOLES
A. S. Shendge* and Dr. D. T. Tayade
One step synthesis of 3-substitutedimino-5-[2-isobutoxy-5-(4-methyl-5-carboxy-1,3-thiazo-2-yl)-
phenylformamidino]-amino-1,2,4-dithiazoles were carried out by oxidative cyclisation of 2-(3-substituted-2,4-
dithiobiureto- formamidino-4-isobutoxyphenyl)-4-methyl-5-carboxy-1,3-thiazoles by making use of liquid bromine
in chloroform medium as an oxidative cyclising agent. The products were isolated, characterized and justified on
the basis of conventional elemental analysis, chemical characteristics and spectral studies.
Keywords: conventional elemental analysis, chemical characteristics and spectral studies.
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