EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

AN OBSERVATIONAL PROSPECTIVE STUDY OF PRESCRIPTION PATTERN OF ANTIMICROBIALS USED IN NEONATAL SEPSIS IN TERTIARY CARE HOSPITAL IN WESTERN RAJASTHAN

Padmaram*, Archana Vyas, Anusuya Gehlot and Monika Sharma

ABSTRACT

Background: Neonatal sepsis is a Clinical syndrome manifested by systemic signs of infection and isolation of bacterial pathogens from bloodstream. Sepsis is the 3rd commonest cause of neonatal death. Neonatal mortality rate in Rajasthan is quite high and data on utilization of antimicrobials for neonatal sepsis is scanty therefore we planned to conduct this study. Method: Study was conducted in NICU of Umaid Hospital, a tertiary care teaching hospital associated with Dr. S. N. Medical College, Jodhpur, Rajasthan. 250 Neonates of either sex admitted to NICU with suspected or confirmed sepsis were included in the study while those neonates admitted in other wards were excluded from study. Appropriate patients were selected by regular visits to NICU and were followed till discharge from NICU. EPI-INFO version 7 software was used for statistical analysis of data. Result: Total 250 cases of neonatal sepsis were studied, of which 148(59.2%) were suspected and 102(40.8%) were confirmed (culture positive) cases. Majority of patients received 2 or 3 antibiotics during the course of therapy. Almost all (97.95%) antibiotics were prescribed by generic names and 77.7% were prescribed from EDL. Most commonly prescribed antibiotics were Ampicillin, Cefotaxime and Amikacin. 85.21% patients were discharged and mortality was 7.6%. Conclusion: Most commonly prescribed antibiotics were Ampicillin, Cefotaxime and Amikacin. Antibiotic utilization studies are good exploratoray tools to know the role of drugs in society and they also create a basis for health care decision making.

Keywords: Drug utilization pattern, Neonatal sepsis.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia