EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 7.065

 ICV - 79.57

Abstract

ANTI-HYPERLIPIDEMIC ACTIVITIES OF METHANOLIC EXTRACT OF MUSK MELON

Rajasree R. S.*, Sibi P. Ittiyavirah and Revathy Krishnan M.

ABSTRACT

Some of the plants, which we consume as part of our diet, are rich in bioactive compounds, which can heal various ailment, or it may supplement the action of the drugs, which we administer. Cucumis melo Linn is a fruit used in a different part of the world. It possesses various medicinal properties. The present study mainly focuses on the anti hyperlipidemic activity of the methanolic extract of muskmelon in high fat diet induced hyperlipidemia in Wistar albino rats. The result reveals a significant reduction in total cholesterol and Low-Density Lipoprotein (LDL). At the same time, an increase in High-Density Lipoprotein (HDL) levels compared to control and positive control group was observed. Combination of standard drug with test also produced a significant effect. The dose of the standard was reduced to half, and it was combined with a low dose of MECM. The results concluded that methanolic fruit extract (400 mg/kg) have potent anti-hyperlipidemic activity in high fat diet-induced hyperlipidemia model, when compared with Simvastatin, treated group.

Keywords: Cucumis melo, Low Density Lipoprotein, High Density Lipoprotein, Cholesterol, Hypolipidemic.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia