EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

SCREENING OF SOLVENT EXTRACT OF PSIDIUM CATTLEIANUM LEAVES FOR ANTICANCER ACTIVITY AGAINST HEPATIC CANCER CELL LINE

Anusree K. V.* and Dhivya R.

ABSTRACT

Plants are used for medical functions since the start of human history and are the basis of modern medicine. From the dawn of ancient drugs, chemical compounds derived from plants are accustomed to treat human diseases. Natural sources have received increasing attention over the past 30 years for their potential as novel cancer preventive and therapeutic agents. In this view the present study was carried out to investigate the anticancer property of acetone extract from Psidium cattleianum leaves against Chang liver cell line by MTT assay, antioxidant activity by DPPH assay and phytochemical analysis was investigated by standard protocols. Results revealed that ethanol extract of P. cattleianum exhibited maximum anticancer activity against Chang liver cell line. A rapid evaluation for antioxidants using DPPH assay demonstrated that leaf extract had excellent free radical scavenging capacity. The phytochemical screening showed the presence of alkaloids, flavonoids, glycosides, phenolic compounds, saponins, tannins and quinones.

Keywords: Anticancer activity; Antioxidant activity; DPPH Assay; Hepatic cancer cell line; MTT assay; Phytochemicals; Psidium; Solvent extracts.

[Full Text Article] [Download Certificate]