SERO-PREVALENCE OF CHIKUNGUNYA VIRUS AMONG ADULT POPULATION IN MANDALAY CITY, MYANMAR
Pa Pa Soe*, Yi Yi Win, Khin Thaw Dar Shein and Win Myint Oo
Context: Chikungunya, a mosquito-borne viral disease, was firstly identified in Tanzania in 1952 and then spread rapidly over 60 countries throughout Asia, Africa, Europe and the Americas since 2004. The global distribution of Chikungunya Virus (CHIKV) shows that this virus is expanding at an alarming rate. Objective: The study aimed to find out the sero-prevalence of CHIKV and associated factors among adult population. Methods: This cross-sectional study was conducted from July to October 2020 among 90 respondents aged over 18 years, who were randomly selected from 6 townships of Mandalay city, Myanmar. Results: Seropositivity rate of CHIKV was 74.44% and those of IgM and IgG were 6.67% and 74.44%, respectively. Seropositivity of female gender (80.36%),high education (76.92%), daily wage worker (88.89%), many family members (84.13%), and lower family income (75.71%), living in a house without mosquito screen (81.08%) were higher than their counterparts. The participants with self-reported history of CHIKV infection, and history of joint pain also had higher seroprevalence (93.33% and 88.24%) than their analogue. Seropositivity was significant for high education (AOR 7.63; 95%CI 3.24–17.02), having ≥4 family members (AOR 3.68, 95%CI 2.97-14.03), being house without mosquito screen (AOR 16.73, 95% CI 2.27-23.14), and those with history of CHIK V infection (AOR 10.89, 95%CI 1.33-19.12) with p <0.05. Conclusion: Seroprevalence survey should be conducted on a regular intermittent premise particularly in individual at risk. People should be encouraged to be aware about the silent infection of CHIKV infection.
Keywords: Sero-prevalence, Chikungunya, adult, Myanmar.
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