EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

TO DEVELOPED COMBINATION OF KETOCONAZOLE AND CURCUMIN TOPICAL DELIVERY LOTION FOR TREATMENT OF FUNGAL INFECTION AND WHITE PATCHES ON SKIN

Chinmay Dahariya*, Anju Mishra, Ghanshyam Rathore and Jhakeshwar Prasad

ABSTRACT

The present study has been undertaken to development of Ketoconazole and Curcumin Topical Delivery Lotion for Treatment of Fungal Infection. Superficial fungal infections of the hair, skin are common yet often difficult to treat. Dermatophytes are one of the most common causes of tinea (capitis, manuum, pedis, cruris, corporis, barbae) and onychomycosis. Candidal infections and pityriasis versicolor, caused by Malassezia furfur, lipophilic yeast, are also among the most widespread superficial cutaneous fungal infections. Topical antifungal agents are compounded into different types of vehicles, such as creams, lotions, gels, or sprays. When applied to the skin surface, they readily penetrate into the stratum corneum to either kill the fungi or inhibit their growth, achieving clinical and mycologic eradication. Ketoconazole belongs to the class of drugs called azole antifungals. It works by stopping the growth of the fungus. The main classes of topical antifungal treatment modalities include the polyenes, the azoles, and the allylamine/benzylamines. Other topical antifungal agents include ciclopirox, a hydroxypyridone, thiocarbonate, haloprogin, and selenium sulfide. The high synergistic activity of combinations is encouraging and the potential drug delivery system for the combination of ketoconazole and Curcumin.

Keywords: Fungal infection; Topical drug delivery systems; Ketoconazole; Curcumin.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )