( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Dr. Ashish Thakur, Dr. R. S. Jhobta, Dr. Ramesh Kaundal and Dr. Seema*


Introduction-Laparoscopic Cholecystectomy is the gold standard procedure for symptomatic cholelithiasis for years Phillipe Mouret of Lyon, France, performed his first laparoscopic cholecystectomy in 1987, followed by Francois Dubois of Paris, France, in 1988.[1,2] For a long time dissection is done with electrosurgical instruments which was first invented by William T Bovie, but with advancements of tools harmonic scalpel is showing promising results. Theoretical benefits for use of harmonic scalpel as dissection technique is less operative time, less bleeding, early post operative recovery, less spillage of stones, less chances of converting into open cholecystectomy, less pain post operatively, less amount of CO2 used. Methods-A comprehensive literature search was performed for trials and studies comparing harmonic scalpel assisted dissection vs electrocautery assisted dissection in laparoscopic cholecystectomy. Results were documented in form of duration of surgery, quantity of CO2 used, intra operative stone spillage, intra operative blood loss, post operative pain at 6 hour and 24 hour after the surgery, duration of hospital stay, any postoperative complications. Result- Operative time, intraoperative bleeding, intraoperative stone spillage, amount of CO2 used and post operative pain all were decreased with use of harmonic ace as compared to electrocautery in most of the studies , however post operative hospital stay and post operative complications are not statiscally reduced with use of harmonic ace as adissection tool. Conclusion-After reviewing various studies it is found that harmonic ace is a better dissecting instrument than electrocautery. Harmonic ace is a costly instrument so cost – benefit ratio is to be evaluated before its use in developing countries. Overall harmonic ace dominate electrocautery in all the testing fields and is a promising new dissection tool.

Keywords: .

[Full Text Article]



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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database