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An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Aribo Ekpe O.*, Amama Ernest A. and Adie Polycarp U.


Thermoxidized palm oil (TPO) and photoxidized palm oil (PPO) have been shown to impact negatively on reproductive function in male Wistar rats. The current studies evaluated effects of these oils on some female reproductive parameters and oxidative status considering variations in hormonal and reproductive functions. Fifteen female Wistar rats weighing 80 - 127 g were divided into 3 groups of 5 rats each. Groups 1 (control), 2 and 3 were fed liberally on plain rat’s feeds, TPO and PPO diets respectively for thirteen weeks. Rats being 19-22 weeks old, were anaesthetized and necessary samples collected for estimation of relevant parameters. Results showed significant reduction in utero-ovarian weight in PPO- (P<0.001) and TPO-fed (P<0.001) groups compared with control. Serum malondialdehyde (MDA) concentration was significantly increased in TPO- (P<0.001) and PPO-fed (P<0.001) groups compared with control and in PPO-fed compared with TPO-fed (P<0.01) groups. Serum catalase (CAT) concentration was significantly reduced in TPO- (P<0.001) and PPO-fed (P<0.001) groups compared with control and in PPO- than TPO-fed (P<0.01) groups. Serum glutathione peroxidase (GPx) concentration was significantly lower in TPO- (P<0.001) and PPO-fed (P<0.001) groups compared with control and in PPO- compared with TPO-fed groups (P<0.01). Serum progesterone was significantly reduced in TPO- (P<0.001) and PPO-fed (P<0.001) groups compared with control. Serum estrogen was significantly higher in TPO- (P<0.001) and PPO- fed (P<0.01) rats compared with control but significantly lower in PPO-fed than TPO-fed (P<0.05) groups. We conclude that TPO and PPO induce oxidative stress and alterations in some reproductive parameters in female Wistar rats.

Keywords: Thermoxidized, photoxidized, palm oil, oxidative stress, reproductive, parameters.

[Full Text Article]




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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database