AN IN-VITRO STUDY IN THE ENHANCEMENT OF CURCUMIN PERMEABILITY WITH PIPERIC ACID ACROSS CACO-2 CELLS
Sreeraj Gopi*, Joby Jacob, Robin George, Sreeraj T.R., Karthik Varma, Mallikarjun, Divya
Low molecular bioavailability of curcumin is a major issue regarding natural pharmacological agents. To overcome
the barriers of bioavailability, many bio-enhancers have been used. Piperine is one among them. To make piperine
more effective in this stream, hydrolyzed piperic acid was prepared and checked for permeability of curcumin.
Keywords: curcumin, Piperine.
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