EVALUATION OF IN VIVO WOUND HEALING ACTIVITY OF ETHANOLIC FLOWERS EXTRACT OF CASSIA TORA LINN

Sangram Keshari Panda*, Aswini Kumar Sethi and Suchismita Pani

ABSTRACT

The plant Cassia tora belonging to family Fabaceae is a annual herb. It is a common plant found in all tropical parts of India and it was previously used in treatment of common skin ailments by Indian tribes. Objectives: The present study was carried out to evaluate the wound healing potential of ethanolic flowers extract of Cassia tora. Materias and methods: These activities were studied by two animal models i.e. Excision and Incision wound model. Soframycin was used as a reference standard and ointment base are used as a control. It was observed that the wound contraction ability of the extract was significantly greater than that of control, which was comparable to that of the reference standard Soframycin ointment Conclusion: The result of the present study indicates that ethanolic flowers extract of Cassia tora posses significant wound healing in excision and incision wound model. The presence of phytoconstituents like alkaloids, flavonoids and phenols either individually or combined may exhibit the synergistic effect towards the healing of wounds.

Keywords: Cassia tora, wound healing, Incision wound, Excision wound.