FACTORS RESPONSIBLE FOR THE RELEASE OF CYTOKINES IN THE MODIFIED PHYSIOLOGICAL PROCESS

Sree Lekshmi R. S.* and Sambath P. S.

ABSTRACT

Cytokines are small proteins that are important for cell signaling. They affect the activity of other cells. They also help in autocrine signaling. Cytokines are produced from immune cells like macrophages, B-lymphocytes, T lymphocytes and mast cells. Cytokines are small secreted proteins released by cells have a specific effect on the interactions and communications between cells. Cytokine is a general name; other names include lymphokine, monokine, chemokine and interleukin. The main function of cytokines is that help in signaling molecules that mediate and regulate immunity, inflammation and hematopoiesis. Cytokines are a large group of proteins, peptides or glycoproteins that are secreted by specific cells of immune system Cytokines play a main role in the natural or innate response by means of the direct action of mechanism aganist the invading agent during the early stages of the infection, or by means of immune modulatory mechanism which activete NK cells and monocytes macrophages, which then induce the release of cytokines.

Keywords: Cytokines, Oxidised Low Density Lipoprotein, Oxysterols, Lysophosphatidylcholine.