EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

HPV INFECTIONS ASSOCIATED WITH ORAL MUCOSA

Dr. Garima Srivastava*, Dr Yadvandra Yadav, Dr. Shilpi Singh, Dr. Mohit Wadhawan, Dr. Md. Shadab Kalim, and Dr Abhishek Sourabh

ABSTRACT

Human papillomavirus (HPV), small non enveloped DNA tumor virus , of papillomavirus family , causes genital warts, common warts, plantar warts and flat warts. Its frequency is about 9-13%. Oral mucosa may play significant role in HPV transmission and its persistent infection in the oral mucosa increase the risk of developing carcinoma. Regular and scrupulous examination of it is most important tool in detecting HPV-associated changes in the oral mucosae . HPV16 being the most prevalent genotype other being HPV 2, 4, 6, 11, 13, 18 and 32. HPV positivity occurs in vermilion border, hard palate, labial mucosa and labial commissures .According to biologic behavior there are various lesions associated with it .Benign lesions being squamous papilloma , verruca vulgaris ,condyloma acuminatum , focal epithelial hyperplasia and premalignant or malignant lesions are leukoplakia, squamous cell carcinoma , lichen planus, verrucus carcinoma. HPV infection is constrained to the basal cells of stratified squamous epithelium, of the oral mucosa the only tissue in which it replicates. The accessible HPV vaccines cover the HPV genotypes found most commonly in the oral mucosa, but their defensive effect against oral cancer remains to be elucidated.

Keywords: HPV infection, oral mucosa, carcinoma, HPV vaccines.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )