EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A STUDY ON EVALUATION OF SERUM FERRITIN LEVELS IN PATIENTS OF HYPERTENSION IN A TERTIARY CARE TEACHING HOSPITAL

Dr. R. P. Sathvika MD*, D. Alamelu Mangai and Dr. T. Kavitha M. D (BIO), DCP

ABSTRACT

Introduction: Elevation of serum ferritin levels leads to serious complications. increased serum ferritin levels lead to increased oxidative stress, further leading to inflammation, endothelial damage and consequently increasing the risk of hypertension. Aim: The aim of the present study was to estimate and compare serum ferritin levels in the hypertensive patients and control group. Material and Methods: The present study was a hospital-based observational and analytical study. The study was conducted over a period of 1 year on 200 patients. The study group comprised of 100 patients (diagnosed with hypertension), and the control group comprised of 100 (age and gender matched) individuals. The levels of serum ferritin were analysed by the Sandwich ELISA method. Result: The results of the present study show that, the mean value of serum ferritin was 272.21±35.67 ng/ml in study group and 69.33 ± 28.12 ng/ml in control group. The mean SBP was 149.65±14.77 mm/Hg in study group and 106.12 ± 6.93 mm/Hg in control group. The mean DBP was 93.4± 9.12 mm/Hg in study group and 70.31±3.62 mm/Hg in control group. The results of the present study indicate that the difference between the mean serum ferritin and mean SBP, mean DBP among the study group and control group was found to be significant statistically (p=<0.05). Conclusion: The present study concluded that elevated serum ferritin level was significantly associated with the incidental risk for hypertension. This finding suggests the value of elevated ferritin level as an early predictor of hypertension.

Keywords: Serum Ferritin, hypertension.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )