EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

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Abstract

IMPACT ON CALCIUM AND MAGNESIUM LEVELS DURING AUTOMATED PLATELETPHERESIS IN NORMAL DONORS

Dr. Atiar Rahman*, Dr. Farah Anjum Sonia, Dr. Sheikh Saiful Islam Shaheen, Dr. Kashfia Islam, Dr. Iffat Ara Akbar, Dr. Zia Uddin Ahmed and Dr. Shahanaj Parveen

ABSTRACT

Background: Utilization of apheretic platelet is increasing day by day due to rapid up gradation of technology in Transfusion Medicine. In Bangladesh requirement of apheretic platelet is increasing due to adoption of advance treatment. Physician are using apheretic platelet due to some advantages over random donor platelet. Though it is a blood donation procedure there is little concern about donor adverse reaction and biochemical changes due to citrate utilization. Objective: The aim of our study was to evaluate biochemical changes especially in Calcium and Magnesium during collection of platelet by apheretic procedure. Our goal was to also evaluate effect of citrate in these two elements. Method: It was a observational study which will be carried out at Transfusion Medicine department, Bangabandhu Sheikh Mujib Medical University, Dhaka from July 2019 to June 2020. Healthy donors was underwent intermittent flow cell separator (MCS 3p, Hemonetics, Braintree, MA, USA). Serum levels of total calcium (tCa ) and Mg (tMg) will be measured before, during and after the procedures. Results: Our study showed that there was significant change in Calcium level (P <0.001). Serum calcium level fell from 9.24±0.72 mg/dl to 8.43±1.38. But after donation there was no significant change in Magnesium level (P=0.939). Conclusion: Our study showed almost 9% reduction of serum calcium level after platelet donation. But there was no significant change in serum Magnesium level which is good sign for aphaeretic platelet donation.

Keywords: Apheretic platelet, biochemical, citrate, anemia, thrombocytopenia.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database Academia