CENTRAL DIABETES INSIPIDUS AS PRESENTING MANIFESTATION OF SUPRACELLAR EPIDERMOID CYST: A CASE REPORT AND LITERATURE REVIEW

Dr. Samia A Bokhari*, Dr. Shaza Khan, Dr. Muneera Al Shareef, Dr. Esraa Bukhari, Dr. Rania Safwat and Dr. Mohammed Bajeri

ABSTRACT

Epidermoid cysts (ECs) are rare intracranial brain tumors. They compromise approximately 1% of intracranial tumors They are slowly growing benign tumors, clinically present with head ache, visual symptoms and anterior pituitary hormonal deficiencies due to mass effect. Polyuria due to central diabetes insipidus(DI) as a presenting clinical manifestation is rare .Only 2 cases was reported in the literature. Here we present a 49 year male presenting with polyuria and visual disturbance. The investigations confirmed presence of Central DI and the MRI brain showed cystic supracellular lesion. He underwent trans sphenoidal surgery and the histopathology confirmed epidermoid cyst. He did well post operatively but the DI persisted after surgery. The epidermoid cysts of sellar region vary in their in presentation depending upon their location and extension into surrounding areas producing mass effect. DI is rare presentation of these rare tumors.

Keywords: Supracellar tumor. Epidermoid cyst, Central diabetes insipidus.