EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

SIGNIFICANCE OF SPECIFIC IMMUNOSSAYS IN DETECTION OF INSULIN ANALOGS IN FACTIOUS HYPOGLYCEMIA IN INVESTIGATION: 3 CASE REPORTS.

Dr. Samia A. Bokahri*, Dr. Sheefa Khan, Dr. Muneera AL Sharref, Dr. Rania Safwat, Amani Mohammed Gusti, Dr. Waleed Bawazeer

ABSTRACT

Objective: The aim is to highlight the importance of integrating specific insulin analog immune assays in the evaluation of hypoglycemic disorder investigations. Methods: We describe clinical, and laboratory findings of three study patients presented with spontaneous hypoglycemia and review the current relevant literature regarding methods of detecting suspicious factious use of insulin analogs by different insulin immunoassays to establish the cause of hypoglycemia. Results: The serum samples taken at the time of hypoglycemia in all three patients showed low insulin and low c-peptide. Mitigating and excluding other causes of hypoglycemia, factitious hypoglycemia due to insulin analogues was suspected. As usual commercial insulin assays don’t detect insulin analogues, Special immunoassays were performed to detect insulin analogues and high insulin levels in these assays confirmed factitious insulin analogue use. Conclusion: Clinicians should be aware of insulin analogues as potential cause of factious hypoglycemia and suitable insulin assays should be included in the algorhythm of investigations of hypoglycemia to detect the commonly used insulin analogues for proper diagnosis and management.

Keywords: Factitious hypoglycemia, insulin analogs, Immunoassay of insulin analogs.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • EJPMR FEBRUARY ISSUE PUBLISHED

    FEBRUARY Issue has been successfully launched on 1 February 2021.

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 February 2021 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )