ASSESSMENT THE RELATIONSHIP OF S. IRON LEVEL AND T3, T4, TSH IN HYPOTHYROID PATIENTS

Maha Fawzi Challab* and Rawya Fawzi Chillab

ABSTRACT

The present work attempts to investigate S. Iron level in sample of patients complaining from hypothyroidism. One hundred and five blood samples for hypothyroidism patients including 17 males and 88 females have been collected during the period November 2018 up to May 2019 from the patient visiting the specialized center for Endocrinology and Diabetes. Their age ranged between 10 to 70 years. The results of the investigations have been compared with those for 37 apparently healthy controls who matched patients in the age and gender. Evaluation of serum concentration of T3, TSH was done by ELASA technique application and T4 was estimated by using ELFA methods, while serum Iron was determined by Bathophenanthrolin method. This study showed that there was a highly significant prevalence of hypothyroidism among age 31-50 years in comparison with other age groups P < 0.01. Moreover, this study revealed that the majority of patients were females 84% in comparison with males 16% with highly significant differences between their frequencies P<0.01. Additionally, highly significant elevation was observed in mean of TSH (17.490μIu\ml) in comparison with control group (2.883μIu\ml) P < 0.01. S. Iron was at the visit (60.561±26.80) with no significant differences in comparison with control (67.054±18.22) P > 0.05. The current study also revealed to that the mean of UIBC and TIBC (269.793±74.555, 327.084±51.258 respectively, and had highly significant differences in comparison with control group (222.621±39.121, 302.027±47.501, respectively. Finally TSH has a weak positive correlation with S. Iron (r=0.038) with anon significant differences P=0.704.

Keywords: T3, T4, TSH, S. Iron, Relationship.