A STUDY OF CORRELATION BETWEEN ABSOLUTE EOSINOPHIL COUNT AND ASTHMA CONTROL IN ADULT PATIENTS

*Dr. S. Rajagopal MD. and Dr. G. Narayanan MD.

ABSTRACT

Introduction: Bronchial Asthma is one of the most common disorders of inflammatory reactions of the respiratory tract, characterized by breathlessness, wheezing, minimal cough and expectoration. Hence aim of our study is to correlate absolute eosinophil count with asthma control in adult. Methods and Methodology: This study was conducted on the patient who attended the Asthma OP in a tertiary care teaching hospital. Patients of 18-75 years were selected for the study. Both the sexes were included and who belong to different socio-economic groups was taken as per inclusion criteria. A total of 40 cases were selected minimum of study was 6months. The statistical analysis made here is based on the data obtained from 40 cases. Results: In our study 57.5% of the asthmatic had increased eosinophil count (more than 450 cell/cumm) and 42.5% had normal absolute eosinophil count and p value 0.000. Mean eosinophil count was high in Uncontrolled asthmatics. Conclusion: Our study shows that serum absolute eosinophil count has a significant impact (p value 0.000) on asthma control, higher levels correlating with poor control, so increased dose or frequent steroid inhalation and dose adjustment, lower absolute eosinophil count well control of asthma. Measurement of absolute eosinophil count can be useful in assessing the severity of such inflammation.

Keywords: Asthma, Eosinophil count, Control.