EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFICACY OF LYCOPENE CAPSULES IN ORAL SUBMUCOUS FIBROSIS

Dr. Nitin Kole, Dr. Mithare Sangmesh, Dr. Paramita Ingle, Dr. Meenal Jethlia, Dr. Pratik Parkarwar, Dr. Rajendra Birangane

ABSTRACT

Oral sub mucous fibrosis is the premalignant condition affecting the oral cavity and most prevailing in youthful generation. The etiology of this condition is consumption of betel nut causing reduce mouth opening, burning sensation and finally the fibrosis of mucosa. The subjects have the symptoms like stiffness of oral mucosa, difficulty in swallowing, alter speech, shrunken uvula. So this condition can be prevented and controlled by stoppage of compution of betel nut, topical and systemic medicines, mouth opening exercises and surgery. In the medicines antioxidant, corticosteroids (topical), turmeric, immused milk, vasodilators are used and found to be effective. The study was undertaken on 50 subjects suffering from Grade I and Grade II OSMF with fifteen days interval and prescribed on Lycopene and placebo for three months. There was significant improvement in burning sensation and mouth opening of OSMF subjects. The study concluded that the administration of Lycopene capsules showed improvement in mouth opening and decrease in the burning sensation in the oral cavity.

Keywords: Oral Submuocus Fibrosis, Premalignant condition, Lycopene Capsules, Stiffness, Burning, Trismus, Betel nut.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )