EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A STUDY ON SERUM LEVEL OF COPPER AND ZINC IN DECOMPENSATED LIVER CIRRHOSIS PATIENTS

Hossain M. S.*, Malek M. A. and Mannan M. B.

ABSTRACT

Introduction: Liver cirrhosis is an end stage condition of liver disease and the leading cause of death for both men and women all over the world. It causes death due to acute or chronic gastrointestinal blood loss & multi organ failure. The aim of the study is to evaluate the serum copper and zinc levels in patients with liver cirrhosis. Methods: A total 120 subjects were included in this study. Among them, 60 diagnosed decompensated liver cirrhosis patients denoted as case group (n=60) and 60 were normal healthy individuals denoted as control group (n=60), both the case and control groups were male because liver cirrhosis occurs rarely female in Bangladesh. The subjects were briefed and written consents were taken. Under all aseptic precaution 5 ml of venous blood was collected from median cubital vein, analysis was carried out in the Department of Biochemistry, Mymensingh Medical College, Mymensingh, over a period of one year from July 2015 to June 2016. All statistical analysis was performed by SPSS windows package, version 20. Significance of the difference between two groups were evaluated by using student‟s unpaired „t‟ test. All the values were expressed as mean ± SD and P value 0.05 was taken as the level of significance. Results: After careful evaluation, in the present study we found significant increase in the serum copper levels and significant decreases in the serum zinc levels in liver cirrhosis patients when compared with that of control group. Conclusion: It can be concluded that to overcome fatal consequences of decompensated liver cirrhosis patients we should avoid high Copper containing food and Zinc supplementation may be beneficial.

Keywords: Liver cirrhosis, Copper, Zinc.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )