EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

EXPLORING DRUG THERAPY PROBLEMS AMONG HYPERTENSIVE PATIENTS VISITING COMMUNITY PHARMACIES

Jeffrey S. Soni* and Azuka C. Oparah

ABSTRACT

Drug therapy problems (DTPs) are a big burden on the healthcare system and there are numerous advantages in resolving them. Our study aimed to identify, determine the prevalence of drug therapy problems and their associated factors among hypertensive patients visiting community pharmacies for prescription refill. A prospective descriptive study was carried out in five randomly selected community pharmacies. Hypertensive patients' prescriptions were assessed for drug therapy problems during the patient's consultation. Data were collected using the pharmaceutical care sheet. The percentage and type of drug therapy problems identified calculated and analyzed using Students' t-test and one way ANOVA at 95% CI. Of 260 hypertensive patients interviewed, 136 (52.3%) were males, 204 (78.5%) married, 108 (41.5%) were below 5 years of hypertension treatment, 205 (33.4%) of the prescribed drugs were two combination anti-hypertensive drugs. A total of 202 (77.7%) DTPs were identified, 135 (65.8%) accounted for adverse drug reactions (ADRs) out of which 47 (35.9%) experienced headache, 32 (24.4%) experienced GIT disturbance and 18 (13.7%) experienced dry cough. 132 (65.3%) Patients had two types of DTPs. Among 202 (77.7%) DTPs encountered 41 (20.3%) and 49 (24.3%) were referred to hospital and community pharmacies respectively. Thirty-four (82.9%) were rejected from the hospital by physicians, while 38(77.6%) were accepted by community pharmacists. Demographic factors and some clinical characteristics number of drugs blood pressure class, number of comorbidity and number of antihypertensive drugs used (P=0.005) significantly affect DTPs. DTPs among hypertensive patients visiting community Pharmacies in Benin City were high and the most occurring DTPs identified resulted from ADRs problem. While the major associated factors were age, sex, number of drugs, blood pressure class, number of comorbidity and number of antihypertensive drugs used.

Keywords: Drug therapy problems (DTPs), community pharmacies, hypertension, patients and associated factors.

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