EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

THE OUTCOME OF MISOPROSTOL FOR THE TREATMENT OF INCOMPLETE ABORTION

Dr. Nasima Begum*, Dr. Rokeya Begum and Dr. Khan Mashrequl Alam

ABSTRACT

Objective: In this study our main aim is to evaluate the outcome of misoprostol for the treatment of incomplete abortion. Method: This hospital based randomized controlled trial study was conducted in in-patient patient Department of Obstetrics and Gynaecology, Chittagong Medical College and Hospital from October 2007 to September 2008. A total of 128 women between the age of 15 to 40 years with diagnosis of first trimester uncomplicated spontaneous incomplete abortion was included in this study. Among them 64 patients were randomized in group ‘A’ as case who were treated with Misoprostol and 64 patients were in group ‘B’ as control who were treated with Manual Vacuum Aspiration. Results: During the study, on day 15 follow up no patient was significantly anemic in any group. But more patients in Misoprostol group (63.3% versus32.25%) complained of mild bleeding or spotting in comparison to MVA group. Also, there was no significant difference in mean Hemoglobin concentration between case and control measured at the end of treatment.Complications like cervical trauma, blood transfusion and others were not reported by any patient. Two patients in Misoprostol group presented as having pelvic infection who were treated with additional antibiotics. Only one patient in MVA group was suspected as a case of iatrogenic uterine perforation identified during the procedure and kept under close observation for 48 hours and necessary investigations were done. As patient’s condition improved, she was discharged after three days. Conclusion: We conclude that, Misoprostol was safer, and more acceptable than MVA to most of the women enrolled in the study.

Keywords: Manual Vacuum Aspiration (MVA), Misoprostol, incomplete abortion.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )