THE OUTCOME OF MISOPROSTOL FOR THE TREATMENT OF INCOMPLETE ABORTION
Dr. Nasima Begum*, Dr. Rokeya Begum and Dr. Khan Mashrequl Alam
Objective: In this study our main aim is to evaluate the outcome of misoprostol for the treatment of incomplete abortion. Method: This hospital based randomized controlled trial study was conducted in in-patient patient Department of Obstetrics and Gynaecology, Chittagong Medical College and Hospital from October 2007 to September 2008. A total of 128 women between the age of 15 to 40 years with diagnosis of first trimester uncomplicated spontaneous incomplete abortion was included in this study. Among them 64 patients were randomized in group ‘A’ as case who were treated with Misoprostol and 64 patients were in group ‘B’ as control who were treated with Manual Vacuum Aspiration. Results: During the study, on day 15 follow up no patient was significantly anemic in any group. But more patients in Misoprostol group (63.3% versus32.25%) complained of mild bleeding or spotting in comparison to MVA group. Also, there was no significant difference in mean Hemoglobin concentration between case and control measured at the end of treatment.Complications like cervical trauma, blood transfusion and others were not reported by any patient. Two patients in Misoprostol group presented as having pelvic infection who were treated with additional antibiotics. Only one patient in MVA group was suspected as a case of iatrogenic uterine perforation identified during the procedure and kept under close observation for 48 hours and necessary investigations were done. As patient’s condition improved, she was discharged after three days. Conclusion: We conclude that, Misoprostol was safer, and more acceptable than MVA to most of the women enrolled in the study.
Keywords: Manual Vacuum Aspiration (MVA), Misoprostol, incomplete abortion.
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