EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A PROSPECTIVE AND COMPARATIVE STUDY OF DIAGNOSTIC ACCURACY OF RADIOLOGICAL AND CYTOLOGICAL STUDY FOR BREAST CARCINOMA IN TERTIARY CARE CENTRE

Suman De, Asis Kumar Saha*, Sajib Chatterjee and Nirjhar Bhattacharya

ABSTRACT

Background: Breast cancer is most common cancer in women worldwide, contributing 25.4% of diagnosed cancer in 2018(1). Radiological and cytological pathways are the two main pathways for investigating breast lump. Radiological investigations include mammography and ultrasonography whereas cytological investigation includes FNAC and core needle biopsy (CNB). The diagnostic accuracy of the above mentioned investigations are not cent percent and have their own merits and demerits. Main aim of our study was to determine and compare the diagnostic accuracy of Mammography, USG of breasts and axillae, FNAC and Core Needle Biopsy in patients presenting with breast lumps with the final histology of excised specimen. Methods: 120 patients with breast lump in our tertiary care centre after meeting the inclusion and exclusion criteria were included in the study. All the patients after through clinical assessment had undergone through USG of breast, mammography, FNAC and core needle biopsy. Findings of above all investigations were compared with final histological findings to assess the sensitivity, specificity and diagnostic accuracy. Results: Sensitivity, specificity, PPV, NPV and diagnostic accuracy are 76.92%, 50.0%, 90.91%, 25.0% and 73.33% for USG of breast whereas mammography revealed 88.46%, 75%, 95.83%, 50% and 86.67%. In respect to FNAC as investigating tool we found sensitivity, specificity, PPV, NPV and diagnostic accuracy are 76.92%, 75.0%, 95.24%, 33.33% and 76.67% whereas core needle biopsy revealed 96.15%, 100%, 100%, 80% and 96.67%. Conclusion: Both radiological and cytological investigation can be well utilized in Triple Assessment method for diagnosis of breast lump with high sensitivity rate.

Keywords: Breast lump, FNAC, Mammography, Core needle biopsy


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )