EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

PRACTICAL APPROACHES TO THE DIAGNOSIS OF SERUM IL-28 LEVELS IN VIRAL HEPATITIS B IN PREGNANT WOMEN

Zufarova Sh. A., Mirzaabdullahozhieva O. U., *Ismailova A. A., Yuldasheva O. S.

ABSTRACT

According to the results carried out since the discovery of interferons, no one doubts that IFN-λ are polyfunctional. The role of IFN-λ as an interferon that suppresses viral infections on the surfaces of the anatomical barriers of the respiratory tract, gastrointestinal tract, blood-brain barrier and liver has been studied quite extensively and in detail. More recently, studies have appeared on the immunomodulatory role of IFN-λ and its direct and indirect effects on the function of immune cells in various inflammatory conditions, thereby explaining the higher safety profile compared to the undesirable pro-inflammatory effects of IFN-α. Interesting data in the field of infectious diseases, as well as the availability of ready-made pegylated forms of IFN-λ, which have already passed clinical studies and showed a higher safety profile in them than pegylated IFN-α, open scientific and clinical horizons for the study and application of IFN-λ. The studies have shown that the values of IFN-gamma and IL-28, which have pronounced antiviral properties, are significantly suppressed during chronic infection with viral hepatitis B. Research in this area will be continued in order to understand the etiopathogenesis, the characteristics of the course of the infectious process and predict the course of the disease.

Keywords: interferons, immunity, antiviral action, interferon system, antiviral protection of immunity, viral hepatitis B.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )