EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

THE TREATMENT OUTCOME OF BREAST CANCER PATIENT

Dr. Abdullah Al Mueed Khan*, Dr. Jobaida Naznin, Dr. Shantanu Das, Prof. Dr. Osul Ahmed Chowdhury

ABSTRACT

Objective: In this study our main goal is to evaluate the treatment outcome of breast cancer patient. Method: This quasi-experimental study was carried out at Dept. of Microbiology, Department of radiotherapy & Department of Surgery, Sylhet MAG Osmani Medical College Hospital from January, 01, 2011 to December, 31, 2011. Samples from the 30 cases were collected, first from Department of surgery (before operative procedure) and then, from Department of radiotherapy (after surgery and 3 cycles of adjuvant chemotherapy) from the same patient. Results: During the study, invasive ductal carcinoma in 28 (93.3%) cases and invasive lobular carcinoma in 2 (6.7%) cases. Lymph node was positive in 18 (60.0%) cases and negative in 12 (40.0%) cases. CD4/CD8 ratio before chemotherapy was 1.7 (SD ± 0.4) and CD4/CD8 ratio after chemotherapy was 1.3 (SD ± 0.5). CD4/CD8 ratio was significantly reduced after chemotherapy than before chemotherapy (Z=3.500; p<0.001). Conclusion: from our study we conclude that, the breast cancer patients demonstrated increased levels of CD4 and CD8+T cells and CD4/CD8 ratio before commencement of any treatment, but the levels were markedly reduced following chemotherapy.

Keywords: breast cancer, CD4/CD8 ratio, chemotherapy.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI )