STUDY ON SERUM LEVEL OF IRON AND ZINC IN TYPE 2 DIABETIC SUBJECTS

Dr. Md. Abdul Malek* and Dr. Md. Shahadath Hossain

ABSTRACT

Introduction: Diabetes mellitus (DM), commonly known as diabetes is a group of metabolic disorders characterized by chronic hyperglycemia resulting from defects in insulin secretion, insulin action, or both. It causes death due to multi organ failure. Excess Iron is associated with DM, increased free radical production leading to oxidative damage to various tissue and organs. Zinc (Zn) helps in insulin secretion as it is a zinc dependents process This study was designed to evaluate the serum Iron and Zinc status in type2 diabetes mellitus patients. Methods: This cross sectional study was done among 60 diagnosed type 2 diabetic patients and 60 healthy people in the Department of Biochemistry, Mymensingh Medical College, Mymensingh over a period of one year from January 2015 to December 2015.Estimation of serum Iron and Zn level were done by colorimetric method by using test kit. All statistical analyses were performed by SPSS windows package, version 20. Significance of the difference between two groups was evaluated by using student’s unpaired ‘t’ test. Results: Study revealed that zinc levels were significantly decreased and iron levels were significantly increased in type2 diabetic patients. Conclusion: It can be concluded that the prevalence of decreased level of zinc and increased level of iron occurs in type2 diabetic patients. So in type 2 diabetic patient’szinc supplementation may be beneficial.

Keywords: Iron, Zinc, Type 2 Diabetes Mellitus.