EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

SPECTROPHOTOMETRY (UV) AND THIN LAYER CHROMATOGRAPHY (TLC) OF TOTAL ALKALOIDS AND GLYCOSIDES OF CUCURBITACINS EXTRACTED FROM A PLANT USED IN THE TREATMENT OF UROGENITAL DISEASES: LAGENARIA SICERARIA

Mahamane Sabiou Sani Maazou*, Lewamy Mamadou, Yaou Chaibou, Aminatou Bako and Haoua Sabo

ABSTRACT

Medicinal plant extracts have always played an essential role as medicines to preserve our health. Lagenaria siceraria is a plant of the cucurbitaceae family widely used in the traditional Nigerian pharmacopoeia. Within the framework of the valorization of this plant, this study focused on the seeds and pulps of six (6) regions of Niger. This work was devoted to the selective extraction of total alkaloids and glycosides of cucurbitacins, thin layer chromatography (TLC) and spectrophotometry of these extracts. The yield of extracts in total alkaloids ranges from 0.2 to 10.51%. The highest yield is obtained with Maradi seeds (10.51%). For cucurbitacin glycosides, the yield varies from 1.88 to 24.80%. The highest yield is obtained with Tillabery pulp (24.80%). TLC and spectrophotometry have shown a wide diversity of chemical compounds with different maximum wavelengths and frontal references. The variation in the yields of total alkaloids and glycosides of cucurbitacins is significant not only according to the parts (seeds and pulp) but also according to the regions.

Keywords: Lagenaria siceraria is a plant of the cucurbitaceae family widely used in the traditional Nigerian pharmacopoeia.


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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing