EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

A PROSPECTIVE STUDY ON ADVERSE DRUG REACTIONS IN CHRONIC KIDNEY DISEASE PATIENTS WITH HYPERTENSION

*Dr. Basavanna P. L, Asna Ashraf, Chethana H. T. and Dr. Niranjan M. R.

ABSTRACT

Hypertension (HTN) is very frequent in patients with renal disease and its prevalence increases as chronic renal failure (CRF) progresses. The prevalence of HTN in renal patients depends fundamentally on the degree of the renal failure and the type of nephropathy, but varies also, as in essential HTN, with age, sex, and body mass index. Objectives: The main objective of the study was to assess the adverse drug reactions in kidney disease patients with hypertension. Materials and Methods: The study was carried at Nephrology department of K R Hospital, Mysore, Karnataka, from April 2020 to September 2020. A total of 84 patients were enrolled in the study as per the inclusion and exclusion criteria. Patient’s demographics data were collected using data collection forms. The adverse drug reactions were analyzed by using Naranjo causality assessment scale and Hartwig’s severity assessment scale. Results: Out of 84 candidates, females show dominance over males. 14 were presented with ADRs (16.7%). Hypokalemia, vomiting & headache and interstistial nephritis were the most commonly reported ADRs. 57.1% of ADRs were mild and 42.9% were moderate. 42.9% of ADRs were probable and 57.1% were in the possible category. Conclusion: The study was conducted to assess the adverse drug reactions found in hypertensive kidney patients. It can be reduced by pharmacist intervention, providing education and awareness about the disease and importance of medication adherence among the study population.

Keywords: Adverse drug reaction (ADR), Chronic Kidney Disease (CKD), Hypertension (HTN) hypokalemia, interstistial nephritis.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing