( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57



Yarmukhamedov A. S., Faizullaeva N. Ya. and Musakhodzhaeva D. A.*


Background: In the structure of infertile marriage, the tendency towards an increase in the male factor and a deterioration in sperm quality dictates the need for a close study of the existing problem. Objective: We examined 72 patients with impaired fertility, who were aged from 26 to 45 years with diagnoses of oligo-, astheno-, teratozoospermia. Methods: Diagnosis verification was carried out on the basis of clinical, instrumental and laboratory research methods. A biochemical analysis of semen was carried out - the level of citric acid, fructose and zinc was studied to assess the functional capabilities of the prostate gland. Result: A significant decrease in the level of citric acid, fructose and zinc in the semen was revealed, as well as a decrease in the level of inhibin B in the blood serum. Conclusion: Summarizing the data presented, we can assume a probable mechanism for the development of shifts associated with impaired fertility, in which there is a decrease in the level of fructose, citric acid and zinc. At the same time, a decrease in the level of inhibin B in the blood serum is observed. All these changes lead to the activation of phospholipase A2, the production of which is indirectly related to the content of zinc ions; this process is due to the activation of free radical processes in the organs of spermatogenesis and ejaculate. Careful monitoring of spermatozoa, the study of their changes at the structural level, as well as the study of biochemical parameters that can discriminate pathological changes are the priority tasks of laboratory diagnostics.

Keywords: semen, fructose, citric acid, zinc, serum inhibin B, sperm motility.

[Full Text Article]




    AUGUST Issue has been successfully launched on 1 August 2022.

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    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing Scholar Article Journal Index (SAJI) International Scientific Indexing ( ISI ) Scope Database