EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Scope Database , Academia ,

ISSN 2394-3211

Impact Factor: 7.065

ICV - 79.57

Abstract

ANTICANCEROS ACTIVITY OF ANNONA MURICATA L LEAVES ON CERVICAL CANCER CELL LINES

Gayathri Krishna K. U.* and Dr. Sr. G. S. Mary Fabiola

ABSTRACT

In this study the anti-cancerous activity of Annona muricata on cervical cancer cell lines was examined. The cytotoxicity was evaluated by direct microscopic analysis and MTTassay. MTTassay reveals that the extraction of A.muricata inhibit the growth of human cervical cancer cell lines. The inverted phase contrast tissue culture microscope (Labomed TCM-400 with MICAPSTM HD camera) displayed cellular shrinkage, granulation, and vacuolization. In summary, The A.muricata has displayed growth inhibitory activity against L6 cells and which induce cell death predominantly via apoptosis and could be exploited as cervical cancer treatment after evaluation.

Keywords: Annona muricata, cervical cancer, L6 cells.

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