EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

European Journal of Pharmaceutical and Medical Research (EJPMR) has indexed with various reputed international bodies like : Google Scholar , Indian Science Publications , InfoBase Index (In Process) , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , International Society for Research activity (ISRA) , Scientific Indexing Services (SIS) , Polish Scholarly Bibliography , Global Impact Factor (GIF) (Under Process) , Universal Impact Factor , International Scientific Indexing (ISI), UAE  , Index Copernicus , CAS (A Division of American Chemical Society) USA (Under Process) , Directory of Open Access Journal (DOAJ, Sweden, in process) , UDLedge Science Citation Index , CiteFactor , Directory Of Research Journal Indexing (DRJI) , Indian citation Index (ICI) , Journal Index (JI, Under Process) , Directory of abstract indexing for Journals (DAIJ) , Open Access Journals (Under Process) , Impact Factor Services For International Journals (IFSIJ) , Cosmos Impact Factor , Jour Informatics (Under Process) , Eurasian Scientific Journal Index (ESJI) , International Innovative Journal Impact Factor (IIJIF) , Science Library Index, Dubai, United Arab Emirates , Pubmed Database [NLM ID: 101669306] (Under Process) , IP Indexing (IP Value 2.40) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , 

 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECT OF DIPEPTIDYL PEPTIDASE 4 INHIBITOR DRUGS IN COMBINATION WITH OTHER MEDICINES IN TYPE 2 DIABETES MELLITUS (T2DM)

Suresh Chandra* and Komal Manwani

ABSTRACT

Dipeptidyl peptidase IV is a focal controller of insulin-animating hormones, glucagon-like peptides, and insulinotropic glucose-subordinate polypeptides. So it's a decent objective for type 2 DM. care, plasma decrease DPP IV protein adds to expanded inherent glucagon, for example, peptide-1, GIP action which at last outcomes in the potentiation of pancreatic islet insulin discharge and ensuing bringing down of blood glucose levels, HbA[1c], glucose emission, the advancement of liver glucose. One of the key objectives of diabetes care is to arrive at restorative methodologies for hemoglobin HbA[1c] and maintain a strategic distance from the inception or decline of a microvascular condition, investigating effectively the DPP IV inhibitor, for example, Sitagliptin and Vildagliptin. A few other novel DPP IV inhibitors are in the pipeline Unless some contraindications for metformin treatment is endorsed and if HbA[1c] targets are not reached after 3 months.several specialist class of drugs could be added in treatment for example, sulfonylurea, Thiazolidinediones, DPP IV inhibitor. Regardless of a wide scope of remedial choices, the accomplishment of HbA[1c] focuses on individuals with diabetes stays testing, with simply over half (52%) of diabetes patients accomplishing a typical HbA[1c] focus of < 7.0%. The present review reveals that the effect of DPP IV inhibitors, combined with other drugs and therapeutic advantages over GLP-1 based approach.

Keywords: Diabetes2 Dipeptidyl Peptidase-4, Glucose-dependent, Polypeptide, Insulinotrophic, Glucagon-like Peptide-1, type 2 Diabetes Mallitus.


[Full Text Article]

INDEXING

NEWS & UPDATION

  • New Issue Published

    Its Our pleasure to inform you that, EJPMR 1 November 2020 Issue has been Published, Kindly check it on http://www.ejpmr.com/home/current_issues

  • EJPMR NOVEMBER ISSUE PUBLISHED

    NOVEMBER 2020 Issue has been successfully launched on 1 November 2020.

  • EJPMR New Impact Factor

    Its our Pleasure to Inform you that EJPMR Impact Factor has been increased from  5.804 to 6.222, due to high quality Publication at International Level

  • Index Copernicus Value

    EJPMR Received Index Copernicus Value 79.57, due to High Quality Publication in EJPMR at International Level

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • Article Invited for Publication

    Article are invited for publication in EJPMR Coming Issue

Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing