EUROPEAN JOURNAL OF
PHARMACEUTICAL AND MEDICAL RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical, Medical & Biological Sciences

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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 ISSN 2394-3211

Impact Factor: 6.222

 ICV - 79.57

Abstract

EFFECT OF PALASH KSHARA ON MICROBIAL LOAD IN INFECTED WOUND WITH SPECIAL REFERENCE TO WOUND BED PREPARATION

*Dr. Govind Meena and Dr. S. J. Gupta

ABSTRACT

Background: Healing of wound is a challenging task to surgeon in ancient time and even in today’s era. Healing is protective mechanism of our body to invade against infection. In modern science many antibacterial formulations are available with their own limitations. non-surgical debridement modalities which were described by Sushruta in context of Vrana chikitsa. Kshar is one of them as effective debridement agent for wound bed preparation. The present study was undertaken to determine the effect of Palash Kshara (Butea monosperma (Lam.) on Microbial load in infected wound wsr to Wound Bed Preparation. This study was conducted for a period of two years from March 2017 to Feb 2019 in Department of Shalya Tantra, Sir Sundar Lal Hospital, IMS, BHU, Varanasi. Aims & Objective: To evaluate the effect of Palash Kshara in infected wound on the basis of Microbial load assessment. Material & Methods: Present study was carried out in total 20 patients of infected wound divided into 2 groups of 10 patients in each, according to drug application used on infected wound. In Group A (Treated Group) Palash Kshara pichu was applied on infected wound, while in Group B(Control Group) patients with infected wound were dressed daily with normal saline. The signs and symptoms of infection were graded before and during the course of treatment. Tissue biopsy to estimate the microbial load prior to and during the course of treatment was done. Result: Palash Kshara pichu as a dressing material is a better than normal saline for the management of Infected wound(Dusta Vrana). This is because the patients treated with Palash Kshara showed faster reduction in Edge, Necrotic Tissue type and amount and Exudate Type and amount, Skin colour surrounding tissue, Peripheral Tissue Edema. The microbial load of the wounds was also reduced significantly. Conclusion: In most of the cases, there was a progressive reduction in the microbial load with time, during the course of treatment indicating the efficacy of the formulation in reducing the microbial load and thus controlling infection, facilitating wound healing.

Keywords: Infected wound, Microbial load, Palash ,Kshara, Vrana shodhana.


[Full Text Article]

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Google Scholar Indian Science Publications InfoBase Index (In Process) SOCOLAR, China Research Bible, Fuchu, Tokyo. JAPAN International Society for Research activity (ISRA) Scientific Indexing Services (SIS) Polish Scholarly Bibliography Global Impact Factor (GIF) (Under Process) Universal Impact Factor International Scientific Indexing (ISI), UAE Index Copernicus CAS (A Division of American Chemical Society) USA (Under Process) Directory of Open Access Journal (DOAJ, Sweden, in process) UDLedge Science Citation Index CiteFactor Directory Of Research Journal Indexing (DRJI) Indian citation Index (ICI) Journal Index (JI, Under Process) Directory of abstract indexing for Journals (DAIJ) Open Access Journals (Under Process) Impact Factor Services For International Journals (IFSIJ) Cosmos Impact Factor Jour Informatics (Under Process) Eurasian Scientific Journal Index (ESJI) International Innovative Journal Impact Factor (IIJIF) Science Library Index, Dubai, United Arab Emirates Pubmed Database [NLM ID: 101669306] (Under Process) IP Indexing (IP Value 2.40) Web of Science Group (Under Process) Directory of Research Journals Indexing