COMBINED EFFECT OF DRIED FIGS WITH JAGGERY IN PHENYLHYDRAZINE INDUCED ANEMIA IN RATS

Anjana Sushma Dixith, R. Padmavathi*, Mohammed Abdul Samad, Kammari Shirisha and P. Ruchitha

ABSTRACT

Anemia is the utmost communal nutritional insufficiency disorder in the world. Anemia can affect many systems in the body and produce a variety of symptoms and signs. The present treatments available for anemia are not safe and effective. Figs and jiggery are conventionally utilized in the treatment of anemia. Hence, the present study was aimed to investigate additive effect of figs and jaggery in phenylhydrazine induced anemia in rats. Phenylhydrazine induced anemia is an effective model to study and evaluate various new therapeutic modalities. In the current study, two days administration of phenylhydrazine has significantly decreased RBC count, hemoglobin, hematocrit levels and increased MCV, MCH, MCHC when compared to normal control group indicating induction of anemia. 28 days treatment with diet supplemented with figs, jiggery and combination of figs and jaggery has significantly increased RBC, hemoglobin, hematocrit levels and decreased MCV, MCH, MCHC levels when compared to anemic control group. Outcomes of the present research work concluded that consuming diet supplemented with figs, jiggery and combination of figs and jaggery could reduce the risk of anemia.

Keywords: Anemia, phenylhydrazine, figs, jaggery, hemoglobin, serum iron.